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• Uva Clemson Football Betting Line
• Osu Football Betting Line

The Syracuse Orange (1-4 overall, 1-3 ACC) and Clemson Tigers (5-0, 4-0) are scheduled to meet at Memorial Stadium in Clemson, S.C., for a noon ET kickoff Saturday (on ACC Network). Below, we analyze the Syracuse-Clemson college football betting odds and lines, with picks and best bets. 10-2 1st in the ACC. The Clemson Tigers' odds to win the 2022 College Football Championship are +350 0.

The Syracuse Orange (1-4 overall, 1-3 ACC) and Clemson Tigers (5-0, 4-0) are scheduled to meet at Memorial Stadium in Clemson, S.C., for a noon ET kickoff Saturday (on ACC Network). Below, we analyze the Syracuse-Clemson college football betting odds and lines, with picks and best bets.

The Tigers are No. 1 in the Amway Coaches Poll powered by USA TODAY Sports.

Syracuse at Clemson: Betting odds and lines

Odds via BetMGM; access USA TODAY Sports’ betting odds for a full list. Lines last updated Tuesday at 6:39 a.m. ET.

Money line: Syracuse +2000 (bet $100 to win $2000) Clemson -10000 (bet $10,000 to win $100)Against the spread/ATS: Syracuse +46 (-110) Clemson -46 (-110)Over/Under: 62.5 (O: +100 U: -121)

Syracuse at Clemson: Three things to know

Syracuse has been a thorn in Clemson’s side over the years. The last time they met in Death Valley, the Tigers eked out a 27-23 win as 24-point favorites on Sept. 29, 2018. Before that, the Orange bumped off the then-No. 2 Tigers 27-24 in Syracuse on Oct. 13, 2017. That Orange team, and the current installment, are night and day, however.The Orange are coming off a 38-21 home loss to Liberty, and they have allowed 38.0 PPG in each of the past two outings while scoring just 22.5 PPG. That’s not good heading into a date with the perennial title contenders of Dabo Swinney.After going 0-3 ATS in the first three contests, Clemson has covered in each of the past two games. The Tigers rolled up 73 points in a road rout of Georgia Tech last weekend, easily covering a 27-point number. Clemson ranks third in the country with 48.4 PPG, while allowing just 12.0 PPG to rank fifth defensively.

Wvu Football Betting Line

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Syracuse at Clemson: Odds, betting lines and picks

Prediction

Clemson 63, Syracuse 10

Money line (ML)

Clemson (-10000) has 99.01% implied odds of winning, so it’s a near certainty that the Tigers pull off a convincing victory. However, why would you ever consider risking $100 for every $1 won? Even in a multi-team parlay this isn’t a good game to include. AVOID.

Against the spread (ATS)

In games when it’s heavily favored, CLEMSON (-46) normally takes its foot off the gas once it gets up comfortably. That was the case in an earlier game against The Citadel, although it certainly wasn’t the case last week in Atlanta. Even when the Tigers pulled their starters for reserves, it was gas pedal to the floor. Expect more of the same this week against Syracuse (+46), which was romped by Liberty at home last Saturday.

Over/Under (O/U)

The OVER 62.5 (+100) could be taken care of by Clemson but itself, and it’s something it easily did last week. The bonus is that playing the Over will cost you even-money, too. The Over has hit in three in a row for Syracuse.

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Uconn Football Betting Line

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Clemson Tigers (8-1) at Virginia Tech Hokies (4-5)

College Football: Saturday, December 5, 2020 at 7:30 pm (Lane Stadium/Worsham Field)

The Line: Virginia Tech Hokies +21.5 -- Over/Under: 66.5Click to Get Latest Betting Odds

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The Virginia Tech Hokies take on the Clemson Tigers in Week 14 ACC college football action from Lane Stadium in Backsburg on Saturday night.

The Clemson Tigers will look to finish the season strong after posting a 52-17 win over Pitt to improve to 8-1 overall and 7-1 in ACC conference play. Trevor Lawrence has thrown for 2,236 yards, 19 touchdowns and 2 interceptions on 70.6% passing while Travis Etienne leads the Tigers in rushing with 692 rushing yards and 12 touchdowns. Amari Rodgers leads Clemson’s receiving group with 58 grabs for 813 yards and 6 scores while Cornell Powell has 594 receiving yards with 4 scores and the aforementioned Etienne has 511 receiving yards. Frank Lawson Jr. and Braden Galloway each have 200+ receiving yards while three more Clemson receivers have at least 100 receiving yards this season. On defense, Baylon Spector leads the Tigers with 49 total tackles including 26 solo tackles and 3.5 sacks while Myles Murphy has 3.5 sacks and Bryan Breese and Trenton Simpson each have 3 sacks this year. Nolan Turner leads Clemson with 3 interceptions as well this season.

The Virginia Tech Hokies are in dire need of a win after losing three straight and 5 of their last 7 games following a 47-14 beatdown loss to Pitt that put V-Tech to 4-5 this season. Hendon Hooker has thrown for 1,332 yards, 9 touchdowns and 5 interceptions on 65.1% passing while also rushing for 627 yards and another 9 scores. Khalil Herbert leads Virginia Tech in rushing with 924 rushing yards as well as 6 touchdowns while Tre Turner has a team-high 31 catches for 504 yards. Tayvion Robinson has 30 grabs for 441 yards and James Mitchell has 357 receiving yards and 4 touchdowns for the Hokies this season. On defense, Chamarri Conner leads Virginia Tech with 70 total tackles including a team-high 54 solo tackles while Justus Reed has a team-high 6.5 sacks. Amare Barrio has 5.5 sacks and Jarrod Hewitt has 4.5 sacks while four different Hokies each have 2 interceptions this season.

Uva Clemson Football Betting Line

Clemson is 12-4 ATS in their last 16 road games and 3-7 ATS in their last 10 games overall while the over is 4-0 in their last 4 games following a win. Virginia Tech is 2-5 ATS in their last 7 games against a team with a winning record and 1-4 ATS in their last 5 games overall while the over is 8-3 in their last 11 games overall. Clemson is 4-1 ATS in the last 5 meetings between these two teams.

Osu Football Betting Line

This is a lot of points to be giving up to Virginia Tech on the surface, but even if it wasn’t Clemson on the other side, the Hokies have lost their last two home games outright as favorites, including the loss to Liberty as a 17-point favorite three weeks ago. Clemson steamrolled Pitt in Trevor Lawrence’s first game back, and with a chance to lock up a rematch with Notre Dame in the ACC title game with a win, I think the Tigers won’t want to leave anything to chance and will put forth a convincing effort here. I’ll lay the points with Clemson on the road in this one.